Lidocaine |
Lidocaine |
C614 |
NCI Thesaurus |
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. |
Other Local Anesthetic (specify) |
Other |
C17649 |
NCI Thesaurus |
Different than the one(s) previously specified or mentioned. |
Procaine |
Procaine |
C61906 |
NCI Thesaurus |
A benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. |