Biomarker lymphocyte assessment type

General Details:

Name:
Biomarker lymphocyte assessment type
Steward:
NINDS
Definition:
Type of biomarker(s) assessed from lymphocytes samples.
Registration Status:
Qualified

Permissible Values:

Value Type:
Value List
Unit of Measure:
Ids:
Value Code Name Code Code System Code Description
OXPHOS enzymology OXPHOS enzymology OXPHOS enzymology
High resolution respirometry High resolution respirometry High resolution respirometry
Coenzyme Q10 Coenzyme Q10 Coenzyme Q10
Intracellular glutathione Intracellular glutathione Intracellular glutathione
DNA strand breaks by comet assay (cultured cells) DNA strand breaks by comet assay (cultured cells) DNA strand breaks by comet assay (cultured cells)
Micronucleus assay followed by fluorescense in situ hybridisation Micronucleus assay followed by fluorescense in situ hybridisation Micronucleus assay followed by fluorescense in situ hybridisation
pyruvate dehydrogenase pyruvate dehydrogenase pyruvate dehydrogenase

Designations:

Designation:
Biomarker lymphocyte assessment type
Tags:
Designation:
Which biomarker(s) were assessed from the specimen's lymphocytes sample?
Tags:
Question Text

Designations:

Definition:
Type of biomarker(s) assessed from lymphocytes samples.
Tags:

Reference Documents:

ID:
Title:
URI:
Provider Org:
Language Code:
Document:
Atkuri, K.R., et al., Inherited Disorders Affecting Mitochondrial Function are Associated with Glutathione Deficiency and Hypocitrullinemia. Proc Natl Acad SCI U S A, 2009. 106(10): P. 3941-5. Kramer, P.A., et al., A Review of the Mitochondrial and Glcolytic Metabolism in Human Platelets and Leukocytes: Implications for their Use as Bioenergetic Biomarkers. REdox Biol, 2014. 2: P. 206-210. Tomasetti, M., et al., Coenzyme Q10 Enrichment Decreases Oxidative DNA Damage in Human Lymphocytes. Free Radic Biol Med, 1999. 27(9-10): P. 1027-32. Migliore, L., ET AL., Evaluation of Cytogenetic and DNA Damage in Mitochondrial Disease Patients: Effects of Coenzyme Q10 Therapy. Mutagenesis, 2004. 19(1): P. 43-9. Naccarati, A., ET AL., Cytogenetic Damage in Peripheral Lympocytes of Mitochondrial Disease Patients. Neurol SCI, 2000. 21(5 SUPPL): P. S963-5. Vallance, H.D., J.R. Toone, and D.A. Applegarth, Measurement of Pyruvate Dehydrogenase (PDHC) in Interleukin-2 (IL-2) Stimulated Lymphocytes. J Inherit Metab Dis, 1994. 17(5): P. 627-8. Fouque, F., et al., Differential Effect of DCA Treatment on the Pyruvate Dehydrogenase Complex in Patients with Severe PDHC Deficiency. Pediatr Res, 2003. 53(5): P. 793-9.

Identifiers:

Source:
NLM
Id:
7J1FeUVqjrC
Version:
1
Source:
NINDS
Id:
C19562
Version:
1
Source:
BRICS Variable Name
Id:
BiomarkLymohAssessTyp
Version: