NIH Common Data Elements (CDE) Repository

General Details:

Name:: PhenX - selenium protocol 050901
Steward:: LOINC
Definition:: The analytical method for serum selenium (Se) is based on inductively coupled plasma mass spectrometry (ICP-MS) using matrix-matched calibration standards. In this method, Se (isotope mass 78 and/or mass 80), and gallium (mass 69) are measured in serum by inductively coupled plasma dynamic reaction cell spectrometry using methane as reaction gas. Strict adherence to quality control (QC) procedures outlined in the Protocol Text is recommended. Controls should be run at the beginning of the day, and then one control analyzed again after approximately each 10 patient samples, and then all QC controls are run at the end of each day's run. Agreement with certified or accepted QC values should be within the +2 S.D. limits.
Registration Status:: Qualified

Value	Code Name	Code	Code System	Code Description

Definition:: The analytical method for serum selenium (Se) is based on inductively coupled plasma mass spectrometry (ICP-MS) using matrix-matched calibration standards. In this method, Se (isotope mass 78 and/or mass 80), and gallium (mass 69) are measured in serum by inductively coupled plasma dynamic reaction cell spectrometry using methane as reaction gas. Strict adherence to quality control (QC) procedures outlined in the Protocol Text is recommended. Controls should be run at the beginning of the day, and then one control analyzed again after approximately each 10 patient samples, and then all QC controls are run at the end of each day's run. Agreement with certified or accepted QC values should be within the +2 S.D. limits.
Tags:: Source: Regenstrief LOINC

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Centers for Disease Control and Prevention, Division of Laboratory Sciences, National Center for Environmental Health Laboratory Procedure Manual for Serum Selenium, August 24, 2004.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Office of Dietary Supplements, National Institutes of Health Dietary Supplement Fact Sheet: Selenium.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Thomson, C. D. (2004). Assessment of requirements for selenium and adequacy of selenium status: A review. European Journal of Clinical Nutrition, 58, 391–402.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Combs, G., Jr., & Gray, W. P. (1998). Chemopreventive agents: Selenium. Pharmacology and Therapeutics, 79, 179–192.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: McKenzie, R. C., Rafferty, T. S., & Beckett, G. J. (1998). Selenium: An essential element for immune function. Immunology Today, 19, 342–345.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Centers for Disease Control and Prevention, National Center for Health Statistics. National Health and Nutrition Examination Survey (NHANES) Overview 2007–2008.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Lockitch, G., Fassett, J. D., Gerson, B., Nixon, D. E., Parsons, P. J., & Savory, J. (1997). Control of pre-analytical variation in trace element determinations; Approved guideline (NCCLS document C38-A). Wayne, PA: National Committee for Clinical Laboratory Standards.

Key:

Related Names

Value:

Key:

Related Codes

Value:

Code System	Code	Code Text	Code Version
https://www.phenxtoolkit.org	50901	selenium

Key:

Fully-Specified Name

Value:

Component	Property	Time	System	Scale	Method
PhenX - selenium protocol 050901	-	Pt	^Patient	-	PhenX

Key:

Basic Attributes

Value:

Class	Type	First Released	Last Updated	Change Reason
PANEL.PHENX	Clinical	Version 2.34	Version 2.66	Updated the PhenX ID from "PhenX." to "PX" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.