Biomarker muscle histology assessment type

General Details:

Name:
Biomarker muscle histology assessment type
Steward:
NINDS
Definition:
Type of biomarker(s) assessed from muscle histology.
Registration Status:
Qualified

Permissible Values:

Value Type:
Value List
Unit of Measure:
Ids:
Value Code Name Code Code System Code Description
Gomori trichrome Gomori trichrome Gomori trichrome
succinate dehydrogenase (SDH) succinate dehydrogenase (SDH) succinate dehydrogenase (SDH)
Cytochrome c Oxidase (COX) (Complex IV) Cytochrome c Oxidase (COX) (Complex IV) Cytochrome c Oxidase (COX) (Complex IV)
Combined SDH+COX Combined SDH+COX Combined SDH+COX
Fibroblast growth factor 21 (fg21) Fibroblast growth factor 21 (fg21) Fibroblast growth factor 21 (fg21)
OXPHOS subunit immunochemistry OXPHOS subunit immunochemistry OXPHOS subunit immunochemistry
Humanin immunochemistry Humanin immunochemistry Humanin immunochemistry

Designations:

Designation:
Biomarker muscle histology assessment type
Tags:
Designation:
Which biomarker(s) were assessed from the specimen's muscle histology?
Tags:
Question Text

Designations:

Definition:
Type of biomarker(s) assessed from muscle histology.
Tags:

Reference Documents:

ID:
Title:
URI:
Provider Org:
Language Code:
Document:
Davis, R.L., et al., Fibroblast Growth Factor 21 is a Sensitive Biomarker of Mitochondrial Disease. Neurology, 2013. 81(21): P. 1819-26. Suomalainen, A., et al., FGF-21 as a Biomarker for Muscle-Manifesting Respiratory Chain Deficiencies: A Diagnostic Study. Lancet Neurol, 2011. 10(9): P. 806-18. Tyynismaa, H., et al., Mitochondrial Myopathy Induces a Starvation-like Response. Hum Mol Genet, 2010. 19(20): P. 3948-58. Filosto, M., et al., Neuropathology of Mitochondrial Diseases. Biosci Rep, 2007. 27(1-3): P. 23-30. Ross, J.M., Visualization of Mitochondrial Respiratory Function Using Cytochrome C Oxidase/Succinate Dehydrogenase (COX/SDH) Double-labeling Histochemistry. J Vis Exp, 2011(57): P. E3266. De Paepe, B., et al., Immunohistochemical Analysis of the Oxidative Phosphorylation Complexes in Skeletal Muscle from Patients with Mitochondrial DNA Encoded tRNA gene Defects. J Clin Pathol, 2009. 62(2): P. 172-6. Kin, T., et al., Humanin Expression in Skeletal Muscles of Patients with Chronic Progressive Extrenal Ophthalmoplegia. J Hum Genet, 2006. 51(6): P. 555-8.

Identifiers:

Source:
NLM
Id:
QJ8mxGV5oS0
Version:
1
Source:
NINDS
Id:
C19567
Version:
1
Source:
BRICS Variable Name
Id:
BiomarkMuscHistAssessTyp
Version: