Was MFI >1000 for donor specific antibody to HLA-A, -B, DRB1 and/or MFI >2000 for HLA-C, DQB1 and DPB1?
General Details:
Name:
Was MFI >1000 for donor specific antibody to HLA-A, -B, DRB1 and/or MFI >2000 for HLA-C, DQB1 and DPB1?
Steward:
NHLBI
Definition:
Code indicating whether the MFI (mean fluorescence intensity) for donor specific antibodies exceeds allowable limit.
Registration Status:
Qualified
Permissible Values:
Data Type:
Value List
Unit of Measure:
Ids:
Value
Code Name
Code
Code System
Code Description
Yes
Yes
No
No
Yes, approved by Protocol Char and/or Protocol Officer
Yes, approved by Protocol Char and/or Protocol Officer
Designations:
Designation:
Was MFI >1000 for donor specific antibody to HLA-A, -B, DRB1 and/or MFI >2000 for HLA-C, DQB1 and DPB1?
Tags:
Designation:
Mean fluorescence intensity donor specific antibody exceed limit indicate code
Tags:
Preferred Question Text
Designations:
Definition:
Code indicating whether the MFI (mean fluorescence intensity) for donor specific antibodies exceeds allowable limit.
Tags:
Short Description,Description
Reference Documents:
ID:
Title:
URI:
Provider Org:
Language Code:
en-us
Document:
Properties:
Key:
Guidelines/Instructions
Value:
SCKLCELL:
HLA antibody presence and specificity will be determined by solid phase immunoassays. An anti-donor specific HLA antibody will be considered positive when the mean fluorescence intensity (MFI) is higher than the cut-off defined by each institution. Recommended cut-off values are MFI >1000 for donor specific antibody to HLA-A, -B, and DRB1 and MFI >2000 for HLA-C, DQB1 and DPB1.
-----
SCKLCELL:
HLA antibody presence and specificity will be determined by solid phase immunoassays. An anti-donor specific HLA antibody will be considered positive when the mean fluorescence intensity (MFI) is higher than the cut-off defined by each institution. Recommended cut-off values are MFI >1000 for donor specific antibody to HLA-A, -B, and DRB1 and MFI >2000 for HLA-C, DQB1 and DPB1.