Ovarian Carcinoma Histologic Primary Classification Type

General Details:

Name:
Ovarian Carcinoma Histologic Primary Classification Type
Steward:
NCI
Definition:
The type of tumor submitted/identified upon slide review.
Registration Status:
Retired

Permissible Values:

Data Type:
Value List
Unit of Measure:
Ids:
Value Code Name Code Code System Code Description
Brenner Tumor, malignant type (WHO code: 9000/3) Malignant Ovarian Brenner Tumor C4270 NCI Thesaurus A Brenner tumor of the ovary characterized by a cytologically malignant cell population and stromal invasion.
Carcinosarcoma (Malignant mullerian mixed tumor) (WHO code: 8950/3) Carcinosarcoma (Malignant mullerian mixed tumor) (WHO code: 8950/3) C34448 NCI Thesaurus A malignant tumor composed of a mixture of carcinomatous and sarcomatous elements.
Clear cell borderline tumor (WHO code: 8310/1) Borderline Ovarian Clear Cell Tumor C40080 NCI Thesaurus An epithelial neoplasm with low malignant potential affecting the ovary. It is characterized by the presence of clear or hobnail cells. In some cases, the cells may display nuclear atypia and prominent nucleoli. When such cells are present, they remain confined to the glands. There is no evidence of stromal invasion.
Clear cell carcinoma (WHO code: 8310/3) Clear Cell Adenocarcinoma C3766 NCI Thesaurus A malignant neoplasm composed of glandular epithelial clear cells. Various architectural patterns may be seen, including papillary, tubulocystic, and solid.
Endometrioid borderline tumor (WHO code: 8380/1) Borderline Ovarian Endometrioid Tumor C7983 NCI Thesaurus A neoplasm of low malignant potential arising from the ovary. It is characterized by the presence of glandular or cystic spaces which contain atypical glandular epithelial cells resembling endometrial cells. The surrounding ovarian stroma is often fibrotic. There is no evidence of stromal invasion.
Endometrioid carcinoma (WHO code: 8380/3) Ovarian Endometrioid Adenocarcinoma C7979 NCI Thesaurus An endometrioid adenocarcinoma arising from the ovary. It comprises 10% to 25% of all primary ovarian carcinomas. Grossly, endometrioid carcinoma may present as a cystic or solid mass. Microscopically, the tumor greatly resembles the appearance of the ordinary type of endometrial adenocarcinoma. As a group, endometrioid carcinoma has a prognosis twice as good as that of serous or mucinous carcinoma.
Granulosa cell tumor (WHO code 8620/1) Ovarian Granulosa Cell Tumor C6261 NCI Thesaurus A granulosa-stromal cell tumor that arises from the ovary. It is characterized by the presence of granulosa cells that comprise at least ten percent of the cellular population. The granulosa cells are often found in a background that contains theca and fibrous cells. There are two major subtypes recognized, adult and juvenile granulosa cell tumor. Clinically, patients may present with an abdominal mass. Symptoms depend on the patient's age. The most important indicator of prognosis is tumor stage. Age over forty years at the time of the initial diagnosis, large tumor size, bilaterality, cellular atypia, and increased mitotic activity are factors indicating a potentially aggressive clinical course and relative poor prognosis.
Malignant germ cell tumor (WHO code: 9064/3) Malignant Ovarian Germ Cell Tumor C4514 NCI Thesaurus An invasive malignant neoplasm that arises from the ovary and originates from primordial germ cells. Representative examples include embryonal carcinoma, yolk sac tumor, dysgerminoma, and non-gestational choriocarcinoma.
Mixed epithelial borderline tumor (WHO code: 8323/1) Borderline Ovarian Mixed Epithelial Tumor C7281 NCI Thesaurus A low grade ovarian epithelial tumor composed of an admixture of two or more of the five major cell types: serous, mucinous, endometrioid, clear cell, and Brenner/transitional. The second or second and third cell types must comprise alone or together at least 10% of the tumor epithelium. The majority of patients present with stage I tumor and a minority present with bilateral disease. Morphologically, it shows papillae with detached cell clusters. Microinvasion may be seen rarely. (WHO 2003)
Mixed epithelial carcinoma (8323/3) Ovarian Seromucinous Carcinoma C40090 NCI Thesaurus A malignant mixed epithelial neoplasm that arises from the ovary and is composed predominantly of serous and endocervical-type mucinous epithelium.
Mucinous borderline tumor, endocervical (seromuninous) type (WHO code: 8472/1) Borderline Ovarian Mucinous Tumor, Endocervical-Like C40038 NCI Thesaurus A neoplasm of low malignant potential arising from the ovary. It is characterized by the proliferation of neoplastic epithelial cells that resemble endocervical epithelial cells. There is no evidence of stromal invasion.
Mucinous borderline tumor, intestinal type (WHO code: 3472/1) Borderline Ovarian Mucinous Tumor, Intestinal Type C40037 NCI Thesaurus A neoplasm of low malignant potential arising from the ovary. It is characterized by the proliferation of neoplastic mucinous epithelial cells that resemble intestinal epithelial cells. There is no evidence of stromal invasion.
Mucinous carcinoma (WHO code: 8480/3) Ovarian Mucinous Adenocarcinoma C5243 NCI Thesaurus An invasive adenocarcinoma that arises from the ovary and is characterized by the presence of malignant epithelial cells that contain intracytoplasmic mucin. There is cellular atypia, increased layering of cells, complexity of glands, and papillary formations.
Mucinous cystadenocarcinoma (WHO code: 8470/3) Ovarian Mucinous Cystadenocarcinoma C4026 NCI Thesaurus An invasive cystic adenocarcinoma arising from the ovary. It is characterized by the presence of malignant glandular epithelial cells which contain intracytoplasmic mucin. The malignant cells invade the ovarian stroma and the cystic spaces contain mucoid material. In a minority of cases both ovaries are involved by the tumor. The prognosis for stage I tumors is excellent. Patients with metastases usually have a poor prognosis.
Other - specify Other C17649 NCI Thesaurus Different than the one(s) previously specified or mentioned.
Other sex cord-stromal tumor (WHO code: 8590/1) OV-STR - 183; Ovary-Stromal C4862 NCI Thesaurus A benign or malignant neoplasm that arises from the ovary and is composed of granulosa cells, Sertoli cells, Leydig cells, theca cells, and fibroblasts. Representative examples include thecoma, fibroma, Sertoli cell tumor, and granulosa cell tumor.
Serous borderline tumor (WHO code: 8441/1) Borderline Ovarian Serous Tumor C5226 NCI Thesaurus A low grade serous epithelial neoplasm arising from the ovary. It is characterized by an atypical proliferation of serous-type epithelial cells without evidence of stromal invasion. It is often asymptomatic but rarely it may present with abdominal pain or abdominal enlargement due to rupture or torsion.
Serous carcinoma (WHO: 8441/3) Ovarian Serous Adenocarcinoma C7550 NCI Thesaurus Ovarian serous adenocarcinoma is a serous neoplasm characterized by nuclear atypia, high mitotic activity, stratification, glandular complexity, branching papillary fronds and stromal invasion. --2002
Serous cystadenocarcinoma (WHO code: 8441/3) Ovarian Serous Cystadenocarcinoma C7978 NCI Thesaurus A malignant serous cystic epithelial neoplasm arising from the ovary. It is characterized by the presence of glandular, papillary, or solid structures. Psammoma bodies may be present. In well differentiated cases the malignant epithelial cells resemble the cells of fallopian tube epithelium. In poorly differentiated cases the malignant epithelial cells show anaplastic features.
Squamous cell carcinoma Ovarian Squamous Cell Carcinoma C40093 NCI Thesaurus A usually high grade squamous cell carcinoma that arises from the ovary and is not associated with a germ cell tumor. The prognosis is poor.
Transitional cell borderline carcinoma (WHO code: 8120/1) Borderline Ovarian Transitional Cell Tumor C40088 NCI Thesaurus An ovarian epithelial neoplasm that resembles the transitional cell neoplasms found in the urinary tract. It is characterized by the presence of atypia and absence of stromal invasion.
Transitional cell carcinoma (WHO code: 8120/3) Ovarian Transitional Cell Carcinoma C5240 NCI Thesaurus A carcinoma that arises from the ovary and is characterized by the presence of malignant epithelial cells that resemble malignant urothelial cells. There is no morphologic evidence of a benign or borderline Brenner tumor component present.
Undifferentiated carcinoma (WHO code: 8020/3) Undifferentiated Ovarian Carcinoma C4509 NCI Thesaurus An aggressive carcinoma arising from the ovary. Most patients present with advanced disease. Microscopically, it is characterized by significant cytologic atypia, increased mitotic activity, and necrosis. The prognosis is usually poor.

Designations:

Designation:
Ovarian Carcinoma Histologic Primary Classification Type
Tags:
Long Name
Designation:
Histologic Type
Tags:
Preferred Question Text

Designations:

Definition:
The type of tumor submitted/identified upon slide review.
Tags:
Long Name
Definition:
Histologic Type
Tags:
Preferred Question Text

Properties:

Key:
caDSR_Context
Value:
BBRB
Key:
caDSR_Short_Name
Value:
OVR_HX_PRI_CLASS_TYP

Identifiers:

Source:
NLM
Id:
m1KGnOJV9bM
Version:
1
Source:
caDSR
Id:
5211051
Version:
1