Lupus SLE proto

General Details:

Name:
Lupus SLE proto
Steward:
PhenX
Definition:
The System Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ARC) Damage Index for Systemic Lupus Erythematosus is a method that physician investigators use to determine the extent of permanent damage to various body organs or organ systems due to lupus or to the treatment thereof. This method is widely used and allows the physician to determine if a person has had any nonreversible changes (i.e., damage) to organ systems. These changes have occurred since a person is being diagnosed with lupus, are not related to active inflammation, and are ascertained via a clinical assessment. Also, unless stated otherwise, these changes must be present for at least six months prior to the assessment. The SLICC /ARC Damage Index is a cumulative index that records damage that occurs in individuals with lupus, regardless of whether the damage can be definitively attributed to lupus or is due to another cause, such as a comorbid condition. Prior to completing this protocol, the PhenX Skin, Bone, Muscle and Joint Working Group (WG) notes that investigators must first confirm the presence of lupus in respondents. This can be done via the PhenX measure Autoimmune Diseases Related to Type 1 Diabetes. This measure uses one question to determine the presence of various autoimmune diseases (including lupus) in respondents or their children.
Registration Status:
Qualified

Designations:

Designation:
Lupus SLE proto
Tags:
Short Name
Designation:
PhenX - systemic lupus erythematosus protocol 171001
Tags:
Long Common Name

Designations:

Definition:
The System Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ARC) Damage Index for Systemic Lupus Erythematosus is a method that physician investigators use to determine the extent of permanent damage to various body organs or organ systems due to lupus or to the treatment thereof. This method is widely used and allows the physician to determine if a person has had any nonreversible changes (i.e., damage) to organ systems. These changes have occurred since a person is being diagnosed with lupus, are not related to active inflammation, and are ascertained via a clinical assessment. Also, unless stated otherwise, these changes must be present for at least six months prior to the assessment. The SLICC /ARC Damage Index is a cumulative index that records damage that occurs in individuals with lupus, regardless of whether the damage can be definitively attributed to lupus or is due to another cause, such as a comorbid condition. Prior to completing this protocol, the PhenX Skin, Bone, Muscle and Joint Working Group (WG) notes that investigators must first confirm the presence of lupus in respondents. This can be done via the PhenX measure Autoimmune Diseases Related to Type 1 Diabetes. This measure uses one question to determine the presence of various autoimmune diseases (including lupus) in respondents or their children.
Tags:
Source: Regenstrief LOINC

Reference Documents:

ID:
Title:
URI:
Provider Org:
Language Code:
en-US
Document:
Gladman, D., Ginzler, E., Goldsmith, C., Fortin, P., Liang, M., Urowitz, M., Bacon, P., Bombardieri, S., Hanly, J., Hay, E., Isenberg, D., Jones, J., Kalunian, K., Maddison, P., Nived, O., Petri, M., Richter, M., Sanchez-Guerrero, J., Snaith, M., Sturfelt, G., Symmons, D., & Zoma, A. (1996). The Development and Initial Validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for Systemic Lupus Erythematosus Arthritis & Rheumatism, 39(3), 363–369.399
ID:
Title:
URI:
Provider Org:
Language Code:
en-US
Document:
Alarcon, G. S., Roseman, J. M., McGwin, G., Jr., Uribe, A., Bastian, H. M., Fessler, B. J., Baethge, B. A., Friedman, A. W., & Reveille, J. D.; the LUMINA Study Group. (2004). Systemic lupus erythmatosis in three ethnic groups. XX. Damage as a predictor of further damage. Rheumatology, 43, 202–205.
ID:
Title:
URI:
Provider Org:
Language Code:
en-US
Document:
Danila, M. I., Pons-Estel, G. J. Zhang, J., Vila, L. M., Reveille, J. D., & Alarcon, G. S. (2009). Renal damage is the most important predictor of mortality within the damage index: data from LUMINA LXIV, a multiethnic US cohort Rheumatology, 48, 542–545.
ID:
Title:
URI:
Provider Org:
Language Code:
en-US
Document:
Lupus in Minorities: Nature versus Nurture (LUMINA) study glossary. Available by contacting one of the study investigators, Dr. Graciela S. Alarcon or Dr. John Reveille.

Properties:

Key:
Related Names
Value:
LELupus SLE protoPan
PanelPANEL.PHENXPanl
PnlPoint in timeRandom
Key:
Related Codes
Value:
Code SystemCodeCode TextCode Version
https://www.phenxtoolkit.org171001systemic_lupus_erythematosus
Key:
Fully-Specified Name
Value:
ComponentPropertyTimeSystemScaleMethod
PhenX - systemic lupus erythematosus protocol 171001-Pt^Patient-PhenX
Key:
Basic Attributes
Value:
ClassTypeFirst ReleasedLast UpdatedChange ReasonPanel Type
PANEL.PHENXClinicalVersion 2.36Version 2.66Updated the PhenX ID from "PhenX." to "PX" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.Panel

Identifiers:

Source:
NLM
Id:
71_CM6njx
Version:
1.0
Source:
PhenX
Id:
171001
Version:
Source:
LOINC
Id:
64392-4
Version:
2.69