Amino acid newborn screen panel

General Details:

Name:
Amino acid newborn screen panel
Steward:
NLM
Definition:
Newborn screening dried blood spot analysis by tandem mass spectrometry (MS/MS) requires pre-processing the specimen with one of two alternative reagent methods referred to as derivatized and non-derivatized (or underivatized) methods. The methods are similar and nearly all analytes and ratios are identical with the limited number of exceptions noted in the description of the LOINC codes. Some labs choose to use the non-derivatized method because it may be faster or less expensive for their operations. There are no analytes which would be interpreted differently based on the method used to process the specimen so there is no need for different LOINC codes for the same compounds based on the reagents. In a few cases, a different LOINC code is used for the derivatized or non-derivatized tandem mass spectrometry (MS/MS) method because based on the reagents used in processing, different analytes are measured or different sets of analytes become isobaric, which means that they cannot be distinguished on the MS/MS because they have the same molecular weight after reagent processing.
Registration Status:
Qualified

Designations:

Designation:
Amino acid newborn screen panel
Tags:
Long Common Name
Designation:
AA NB scn Pnl DBS-sCnc
Tags:
Shortname

Designations:

Definition:
Newborn screening dried blood spot analysis by tandem mass spectrometry (MS/MS) requires pre-processing the specimen with one of two alternative reagent methods referred to as derivatized and non-derivatized (or underivatized) methods. The methods are similar and nearly all analytes and ratios are identical with the limited number of exceptions noted in the description of the LOINC codes. Some labs choose to use the non-derivatized method because it may be faster or less expensive for their operations. There are no analytes which would be interpreted differently based on the method used to process the specimen so there is no need for different LOINC codes for the same compounds based on the reagents. In a few cases, a different LOINC code is used for the derivatized or non-derivatized tandem mass spectrometry (MS/MS) method because based on the reagents used in processing, different analytes are measured or different sets of analytes become isobaric, which means that they cannot be distinguished on the MS/MS because they have the same molecular weight after reagent processing.
Tags:
TERM DEFINITION/DESCRIPTION(S)

Properties:

Key:
RELATED NAMES
Value:
AA NB scn PnlLevelScn
AcdNB scn AAScr
AcidsNew bornScrn
BloodPanSubstance concentration
ChemistryPANEL.CHEMISTRYWB
DBSPanlWhole blood
Dried blood spotPnl
Filter paperPoint in time
FPRandom
Key:
Fully-Specified Name
Value:
ComponentPropertyTimeSystemScaleMethod
Amino acid newborn screen panelSCncPtBld.dot-
Key:
BASIC ATTRIBUTES
Value:
Class/TypePanel TypeCreated OnLast Updated in VersionOrder vs ObsStatus
PANEL.CHEM/LabPanel2008/05/152.40OrderActive
Key:
LOINC_Copyright
Value:
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, LOINC panels and forms file, LOINC linguistic variants file, LOINC/RSNA Radiology Playbook, and LOINC/IEEE Medical Device Code Mapping Table are copyright © 1995-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/terms-of-use.
Key:
PublicDomain
Value:
true

Identifiers:

Source:
NLM
Id:
my0cTMpLG
Version:
Source:
LOINC
Id:
53261-4
Version:
2.56